In 1969, the Ghana Medical School was formally incorporated into the University of Ghana Medical School (UGMS). In that same year, the first 39 graduating students of the School were awarded University of Ghana degrees.
In 1974, the GMS now SMD (School of Medicine and Dentistry) initiated the development of a Dental School. The Basic Dental Science courses were offered at the Medical School while clinical programmes were pursued at the University of Lagos, Nigeria, the University of Manchester and the University of London, U.K. In 1992, the clinical courses became fully localized. The University therefore granted Dentistry a faculty status. The first batch of locally produced dental surgeons graduated in 1997.
In 1979, the Noguchi Memorial Institute for Medical Research (NMIMR) was established with sponsorship from the Japan government through the Ministry of Finance and Economic Planning. This Research Institute was sited on the plot of the University of Ghana earmarked for the permanent medical school.
In 1994, the School of Medicine and Dentistry, in collaboration with the Ministry of Health, brought into being the School of Public Health for graduate courses leading to the award of MPH, MPhil and PhD degrees. This School is currently located in rooms of the Institute of Statistical, Social and Economic Research and in the Department of Statistics. Permanent building for the School has started with the construction of the Bill Gates Centre for Malaria Research and Control at the site for the medical complex at the main University.
The Ministry of Health, in 1998, initiated the establishment of a School of Allied Health Sciences now (SBAHS) School of Biomedical and Allied Health Sciences, to train graduate allied health Professionals . Programmes for this school include physiotherapy, medical laboratory science and radiography. The Academic Board and the University Council approved this proposal in 1999. In the year 2001, this School came into being. An earlier Diploma in Medical Laboratory Technology also sponsored by the Ministry of Health in 1994 was phased out, with the birth of the School of Biomedical and Allied Health Sciences.
The idea of creating a College of Medicine was mooted in 1994. Planning for the College took five (5) years. In 1997, the Academic Board of the University endorsed proposals from the UGMS to bring together School of Medicine and Dentistry, the School of Public Health, Noguchi Memorial Institute for Medical Research, the School of Biomedical and Allied Health Sciences and a School of Nursing as a College of Medical Sciences.
On December 11, 1999, the University Council gave assent to the establishment of the College but changed the name to COLLEGE OF HEALTH SCIENCES.
Schedule D of the University of Ghana Statutes that established the SMD was therefore amended to bring the College into being.